ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research
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ACCEL Lite: Featured ACCEL Interviews on Exciting CV Research
The American College of Cardiology offers select interviews and summaries of cardiology's most interesting research areas from ACCEL's renowned library, hosted by ACCEL Editor-in-Chief Alison L. Bailey, MD, FACC, FAACPVR.
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Key Take-Home Messages From the 2025 Sports Cardiology Guidelines
There is increasing emphasis on shared decision-making when evaluating sports participation for competitive athletes with cardiovascular disease, refl...
Insights From the CADENCE Trial
In the CADENCE proof-of-concept study, sotatercept demonstrated meaningful improvements in pulmonary vascular and cardiac hemodynamics in patients wit...
A Look At The ORBITA-CTO Trial
The ORBITA-CTO trial was a multicenter, randomized, double-blinded study that enrolled 50 patients with symptomatic single-vessel chronic total occlus...
THRIVE Food is Medicine Pilot Trial: Addressing Hypertension Through Produce Prescriptions
The American Heart Association–funded THRIVE Food is Medicine pilot trial demonstrated strong promise in addressing hypertension through produce presc...
Inflammation in CVD: A 2025 ACC Scientific Statement
Inflammation has emerged as a critical contributor to the pathogenesis and clinical outcomes of cardiovascular disease (CVD), with growing evidence hi...
Lower LDL-C for Longer? Defining the Optimal Timing and Intensity of Rx
Should statin therapy be routinely initiated in middle‑aged adults with at least one atherosclerotic cardiovascular disease risk factor and LDL‑C leve...
Keeping it Simple: Top 10 Things to Know About the 2026 Dyslipidemia Guideline
The 2026 ACC/AHA Dyslipidemia Guidelines highlight that Lp(a) confers a graded ASCVD risk, with levels around 125 nmol/L (50 mg/dL) indicating meaning...
Heart and Liver Health: Interconnectedness of CV and Hepatic Risk
ardiac and hepatic function are closely interconnected, with deterioration in one organ often accelerating disease progression in the other. Emerging...
Addressing Cardiovascular-Kidney-Metabolic Syndrome Health
Cardiovascular-Kidney-Metabolic (CKM) syndrome encompasses a spectrum of interconnected cardiovascular, kidney, and metabolic conditions that progress...
Sotatercept: New Therapies for PAH
Pulmonary arterial hypertension (PAH) remains a devastating, progressive disease with high morbidity and mortality despite advances in targeted therap...
Does Eliminating Coffee Avoid Fibrillation (DECAF) Trial
Caffeinated coffee may reduce the risk of atrial fibrillation through several proposed mechanisms, including improved autonomic balance, antioxidant e...
Evaluating the 2025 AHA/ACC High Blood Pressure Guideline
The 2025 High Blood Pressure Guideline introduces key updates to the 2017 recommendations, reflecting the evolving understanding of hypertension and i...
Cardiovascular-Kidney Therapies in CKD
Heart and kidney disease are closely linked, as individuals with chronic kidney disease (CKD) face a significantly higher risk of cardiovascular event...
Prasugrel Benefits Patients With Diabetes and Multivessel Disease Post-PCI: TUXEDO-2 Trial
The findings from the TUXEDO‑2 trial provide important clinical insights for managing high‑risk patients with diabetes and multivessel coronary diseas...
The Power of Nutrition: GOFRESH Trial
The GOFRESH trial showed that providing DASH‑patterned groceries through a structured grocery‑ordering strategy meaningfully lowered systolic blood pr...
OCEAN Trial: Antithrombotic Therapy after Successful Catheter Ablation for Atrial Fibrillation
The OCEAN Trial found that rivaroxaban did not significantly reduce the incidence of stroke, systemic embolism, or new covert embolic events compared...
NOTIFY-PICTURE Trial: Real-Time Notification of AI-Derived Incidental CAC on Statin Initiation
What exactly is incidental coronary artery calcification, and what does it mean when artificial intelligence identifies these calcifications? Incident...
VESALIUS-CV Trial: Effect of Evolocumab in Patients at CV Risk without Prior MI or Stroke
The VESALIUS‑CV trial demonstrated that adding the PCSK9 inhibitor evolocumab to optimized lipid‑lowering therapy significantly reduced the risk of fi...
ACCEL Lite: Hypertension Treatment Trials in the Elderly for Brain Health
Is the evidence convincing that intensive antihypertensive therapy protects brain function and helps prevent dementia? Research increasingly shows tha...
ACCEL Lite: SURPASS-CVOT: Effect of Tirzepatide Versus Dulaglutide on MACE
In patients with Type 2 diabetes and established atherosclerotic cardiovascular disease (ASCVD), tirzepatide was non‑inferior to dulaglutide for major...
CAUGHT-CAD: Combining Coronary Calcium Score with Treatment on Plaque Progression in Familial CAD
Coronary artery calcium (CAC) scoring provides important prognostic value, particularly for individuals at intermediate risk for coronary artery disea...
AI-Enabled Nationwide Opportunistic Screening of Non-Contrast Chest CT for Death and CV Outcomes
AI technology transforms routine chest computed tomography (CT) scans by precisely quantifying—rather than simply detecting—key cardiovascular imaging...
ACCEL Lite: Should There Be a Reappraisal of Surgical Threshold in Patients with AA Dilation?
Ascending aortopathy (AA) is typically asymptomatic and often diagnosed incidentally, with surgical aortic replacement recommended once aneurysmal thr...
Top Takeaways from 2025: Preventive Cardiology with C. Noel Bairey Merz, MD, MACC
In this interview, C. Noel Bairey Merz MD, MACC and Alison L. Bailey, MD FACC, discuss the Top Preventive Cardiology Takeaways from 2025 including tri...
Top Takeaways from 2025: EP with DJ Lakkireddy, MBBS, FACC
In this interview, DJ Lakkireddy, MBBS, FACC and Alison L. Bailey, MD FACC, discuss the Top Electrophysiology Takeaways from 2025 including trials CLO...
Multimodality Imaging in Inflammatory Cardiomyopathy
Multimodality imaging plays a pivotal role in evaluating inflammatory cardiomyopathy, particularly when cardiac sarcoidosis (CS) is suspected. Symptom...
Top Takeaways from 2025: Clinical Cardiology with Allen J. Taylor, MD, FACC
In this interview, Allen J. Taylor, MD, FACC and Alison L. Bailey, MD FACC, discuss the Top Clinical Cardiology Takeaways from 2025 including trials S...
Top Takeaways from 2025: Interventional Cardiology with Deepak Bhatt, MD, MPH, MBA, FACC
In this interview, Deepak Bhatt, MD, MPH, FACC and Alison L. Bailey, MD FACC, discuss the Top Interventional Cardiology Takeaways from 2025 including ...
PANTHER-P2Y12 Inhibitor or Aspirin moNoTHERapy as Secondary Prevention in Patients with CAD
he PANTHER study indicates that clopidogrel provides superior protection against major cardiovascular events compared to aspirin in patients with coro...
ACCEL Lite: Top Takeaways from 2025: HF with Clyde Yancy MD, MSc, MACC
In this interview, Clyde Yancy MD, MSc, MACC and Alison L. Bailey, MD FACC, discuss the Top Heart Failure Takeaways from 2025 including trials SUMMIT...
ACCEL Lite: Top Takeaways from 2025: CV Imaging with Amit R. Patel, MD, FACC
In this interview, Amit R. Patel, MD, FACC and Alison L. Bailey, MD FACC, discuss the Top Cardiovascular Imaging Takeaways from 2025 including myocard...
C-Reactive Protein and CV Risk in the General Population
Inflammation is a key contributor to cardiovascular disease (CVD), influencing both its onset and progression. High-sensitivity C-reactive protein (hs...
ALONE-AF: Discontinuing Long-Term Oral Anticoagulation After Successful AFib Ablation
The ALONE-AF study examined outcomes in atrial fibrillation (AF) patients who remained free of recurrence following catheter ablation. Researchers fou...
How Does Imaging Guide Management in Patients with Obesity?
Imaging is a powerful tool in managing obesity, helping clinicians visualize fat distribution and detect complications like fatty liver disease or hea...
TACSI Trial: Dual or Single Antiplatelet Therapy After CABG in Patients With ACS
In the TACSI trial, researchers evaluated ticagrelor plus aspirin versus aspirin alone in about 2,200 patients who underwent coronary artery bypass gr...
VICTORION-Difference: Inclisiran-Based Strategy vs. Standard of Care
Current clinical challenges in lipid control include achieving and maintaining target LDL-cholesterol levels in patients at high risk for atherosclero...
Aortopathies: What A Cardiologist Needs to Know
What if your genes could predict a life-threatening condition before symptoms ever appear? Explore how medical science uncovered the genetic roots of...
PhysioSync-HF: Conduction System vs. Biventricular Pacing in Cardiac Resynchronization in HFrEF
Can a newer, more targeted pacing method revolutionize heart failure treatment? The PhysioSync-HF trial investigates conduction system pacing as a pot...
DAPT-SHOCK-AMI Trial: Cangrelor in Cardiogenic Shock
The DAPT SHOCK AMI trial is the first major study to evaluate antiplatelet therapy specifically in patients with cardiogenic shock (CS) following acut...
ODYSSEY-HCM: Mavacamten in nHCM
The ODYSSEY-HCM trial found that mavacamten did not significantly improve exercise capacity or patient-reported outcomes in individuals with symptomat...